The Ugi three-component reaction and its variants
Julio C. Flores-Reyes, Alejandro Islas‐Jácome, Eduardo González‐Zamora
Abstract
A broad variety of α-aminoamide-based compounds have been synthesized via the three-component version of the Ugi reaction (U-3CR) or by any of its variants (Ugi-Zhu-3CR, Orru-3CR, Ugi-4C-3CR, Ugi-Joullié-3CR, GBB-3CR, Ugi-Reissert-3CR, and so on).
Topics & Concepts
Ugi reactionChemistryComponent (thermodynamics)IsocyanideMedicinal chemistryPhysicsThermodynamicsMulticomponent Synthesis of HeterocyclesChemical Synthesis and AnalysisSynthesis and biological activity