CD19-positive lymphocyte count is critical for acquisition of anti-SARS-CoV-2 IgG after vaccination in B-cell lymphoma
Akinao Okamoto, Hidetsugu Fujigaki, Chisako Iriyama, Naoe Goto, Hideyuki Yamamoto, Keichiro Mihara, Yoko Inaguma, Yasuo Miura, Katsuya Furukawa, Yukiya Yamamoto, Yoshiki Akatsuka, Senji Kasahara, Kotaro Miyao, Masutaka Tokuda, Seiko Sato, Yuki Mizutani, Michiko Osawa, Kéiko Hattori, Sachiko Iba, Ryoko Kajiya, Masataka Okamoto, Kuniaki Saito, Akihiro Tomita
Abstract
] However, there is still limited information about the conditions under which such patients may acquire antibodies after vaccination. In this study, we conducted a prospective observation study (registered on the University Hospital Medical Information Network [UMIN] as #000045150) to evaluate antibody titers achieved after SARS-CoV-2 vaccination in patients with hematological diseases, focusing on peripheral blood lymphocyte subsets and g-globulin levels, to evaluate the response and search for markers that predict the response.