Litcius/Paper detail

Borate-catalysed direct amidation reactions of coordinating substrates

Richard J. Procter, Carla Alamillo‐Ferrer, Usman Shabbir, P L Britton, Dejan‐Krešimir Bučar, Alexandre S. Dumon, Henry S. Rzepa, Jordi Burés, Andrew Whiting, Tom D. Sheppard

2025Chemical Science14 citationsDOIOpen Access PDF

Abstract

catalyst generation from commercially available reagents renders the process readily accessible for everyday laboratory use. Further experiments showed that the deactivating effect of 2-aminopyridine on boronic acid catalysts was due to its ability to stabilise catalytically inactive boroxines.

Topics & Concepts

BoronChemistryCombinatorial chemistryOrganic chemistryChemical Synthesis and AnalysisChemical Synthesis and ReactionsAntimicrobial Peptides and Activities