Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
Gerlis von Haugwitz, Xu Han, Lara Pfaff, Qian Li, Hongli Wei, Jian Gao, Karen Methling, Yu‐Fei Ao, Yannik Brack, Jan Mičan, C. Feiler, M.S. Weiss, David Bednář, Gottfried J. Palm, Michael Lalk, Michael Lammers, Jiřı́ Damborský, Gert Weber, Weidong Liu, Uwe T. Bornscheuer, Ren Wei
Abstract
PETase and one-fourth of the reaction time to yield the same amount of TPA under similar PET degradation conditions. Our simple dual enzyme system reveals further advantages in terms of cost-effectiveness and catalytic efficiency since it does not require time-consuming and expensive cross-linking and immobilization approaches.
Topics & Concepts
DepolymerizationHydrolysisChemistryPolyethylene terephthalateCarboxylesteraseMonomerCatalysisOrganic chemistryPolymer chemistryEnzymePolymerMaterials scienceComposite materialMicroplastics and Plastic Pollutionbiodegradable polymer synthesis and propertiesEffects and risks of endocrine disrupting chemicals