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Recent advances in transition-metal-catalyzed carbene insertion to C–H bonds

Yuan He, Zilong Huang, Kaikai Wu, Juan Ma, Yong‐Gui Zhou, Zhengkun Yu

2022Chemical Society Reviews336 citationsDOI

Abstract

)-H, and alkynyl C(sp)-H, as well as asymmetric carbene insertion to C-H bonds, and more coverage will be given to the recent work. Due to the rapid development of the C-H functionalization area, future directions in this topic are also discussed. This review will give the authors an overview of carbene insertion chemistry in C-H functionalization with focus on the catalytic systems and synthetic applications in C-C bond formation.

Topics & Concepts

CarbeneCatalysisTransition metalChemistryInsertion reactionMetalStereochemistryCombinatorial chemistryOrganic chemistryCyclopropane Reaction MechanismsCatalytic C–H Functionalization MethodsSynthesis and Catalytic Reactions
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