Oral recombinant methioninase increases TRAIL receptor-2 expression to regress pancreatic cancer in combination with agonist tigatuzumab in an orthotopic mouse model
Jun Yamamoto, Kentaro Miyake, Qinghong Han, Yuying Tan, Sachiko Inubushi, Norihiko Sugisawa, Takashi Higuchi, Yoshihiko Tashiro, Hiroto Nishino, Yuki Homma, Ryusei Matsuyama, Sant P. Chawla, Michael Bouvet, Shree Ram Singh, Itaru Endo, Robert M. Hoffman
Topics & Concepts
Pancreatic cancerAgonistCancerCancer researchMethionineCancer cellApoptosisMedicineReceptorIn vitroInternal medicineEndocrinologyBiologyBiochemistryAmino acidCancer Research and TreatmentsVirus-based gene therapy researchCancer-related Molecular Pathways