Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections
Simone A. Thair, Yudong D. He, Yehudit Hasin-Brumshtein, Suraj Sakaram, Rushika Pandya, Jiaying Toh, David Rawling, Melissa Remmel, Sabrina Coyle, George Ν. Dalekos, Ioannis Koutsodimitropoulos, Glykeria Vlachogianni, Eleni Gkeka, Eleni Karakike, Georgia Damoraki, Nikolaos Antonakos, Purvesh Khatri, Evangelos J. Giamarellos‐Bourboulis, Timothy E. Sweeney
Abstract
natural killer cells and M2 macrophages. The concordant and discordant responses mapped out here provide a window to explore the pathophysiology of the host response to SARS-CoV-2.
Topics & Concepts
RhinovirusVirologyCoronavirusDengue feverBiologyMiddle East respiratory syndrome coronavirusPandemicImmune systemImmunologyTranscriptomeCoronavirus disease 2019 (COVID-19)VirusGeneDiseaseMedicineInfectious disease (medical specialty)Gene expressionGeneticsInternal medicineCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchRespiratory viral infections research