Psychiatric Comorbidities in People With Epilepsy
Marco Mula, Andrés M. Kanner, Nathalie Jetté, Josemir W. Sander
Abstract
PURPOSE OF REVIEW: To review the latest evidence concerning the epidemiology, clinical implications, and management of psychiatric disorders in epilepsy. RECENT FINDINGS: People with epilepsy have a 2-5 times increased risk of developing any psychiatric disorder, and 1 in 3 patients with epilepsy have a lifetime psychiatric diagnosis. Psychiatric comorbidities represent a poor prognostic marker as they have been associated with a poor response to treatment (drugs and surgery), increased morbidity, and mortality. Validated screening instruments are available for mood and anxiety disorders in adults as well as attention-deficit hyperactivity disorder in children with epilepsy. SUMMARY: All patients with epilepsy should be routinely screened for psychiatric disorder at the onset and at least once a year. Patients with epilepsy and their relatives should be informed of the risk of mental health problems and the implications.