New thiazole-based derivatives as EGFR/HER2 and DHFR inhibitors: Synthesis, molecular modeling simulations and anticancer activity
Mohamed Sabry, Mariam A. Ghaly, Azza R. Maarouf, Hussein I. El‐Subbagh
Topics & Concepts
ChemistryThiazoleCytotoxicityKinaseApoptosisEGFR inhibitorsPharmacologyIC50Cell cycleIn vivoCancer cellIn vitroCancerBiochemistryStereochemistryEpidermal growth factor receptorReceptorBiologyBiotechnologyGeneticsSynthesis and biological activityHER2/EGFR in Cancer ResearchClick Chemistry and Applications