Elucidating Conformation and Hydrogen-Bonding Motifs of Reactive Thiourea Intermediates
Amelie A. Ehrhard, Lucas Gunkel, Sebastian Jäger, Arne C. Sell, Yuki Nagata, Johannes Hunger
Abstract
substitution. Our results highlight the subtle interplay between conformational equilibria, bonding states, and bonding lifetimes in reactive intermediates in thiourea catalysis, which help rationalize their catalytic activity.
Topics & Concepts
ChemistryHydrogen bondPhotochemistryCatalysisMoietyInfrared spectroscopyCrystallographySubstrate (aquarium)ThioureaStereochemistryMoleculeOrganic chemistryOceanographyGeologyMolecular Spectroscopy and StructureCrystallography and molecular interactionsMolecular spectroscopy and chirality