Reversal of TGFβ1-Driven Profibrotic State in Patients with Pulmonary Fibrosis
Harold A. Chapman, Ying Wei, Genevieve Montas, Darren Leong, Jeffrey A. Golden, Binh N. Trinh, Paul J. Wolters, Claude Jourdan Le Saux, Kirk D. Jones, Nancy K. Hills, Elena Foster, Justin M. Oldham, A. Linderholm, Prerna Kotak, Martin Decaris, Scott Turner, Jin-Woo Song
Abstract
EGCG and Pulmonary Fibrosis Nine patients who were scheduled to undergo lung biopsy for pulmonary fibrosis were given epigallocatechin gallate (EGCG) for 2 weeks. Levels of fibrotic markers in lung...
Topics & Concepts
MedicinePulmonary fibrosisFibrosisLungBiopsyLung fibrosisInternal medicineTransforming growth factorLung biopsyPathologyGastroenterologyGallatePharmacologyInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisCardiac Fibrosis and RemodelingChronic Obstructive Pulmonary Disease (COPD) Research