STING is an intrinsic checkpoint inhibitor that restrains the TH17 cell pathogenic program
Luis Eduardo Alves Damasceno, Guilherme Cesar Martelossi Cebinelli, Mariane Font Fernandes, Daniele C. Nascimento, Gabriel Azevedo Públio, Marco Aurélio Ramirez Vinolo, Sérgio C. Oliveira, Tim Sparwasser, Thiago M. Cunha, Fernando Q. Cunha, José C. Alves‐Filho
Abstract
17-cell-mediated inflammation.
Topics & Concepts
Stimulator of interferon genesStingCell biologyBiologySignal transductionT cellContext (archaeology)Immune systemImmunologyInnate immune systemPaleontologyEngineeringAerospace engineeringinterferon and immune responsesInflammasome and immune disordersImmune Response and Inflammation