Peptides Isolated from Amphibian Skin Secretions with Emphasis on Antimicrobial Peptides
Xi Chen, Songcai Liu, Jiayuan Fang, Shuo Zheng, Zhaoguo Wang, Yingying Jiao, Peijun Xia, Hongyan Wu, Ze Ma, Linlin Hao
Abstract
The skin of amphibians is a tissue with biological functions, such as defense, respiration, and excretion. In recent years, researchers have discovered a large number of peptides in the skin secretions of amphibians, including antimicrobial peptides, antioxidant peptides, bradykinins, insulin-releasing peptides, and other peptides. This review focuses on the origin, primary structure, secondary structure, length, and functions of peptides secreted from amphibians' skin. We hope that this review will provide further information and promote the further study of amphibian skin secretions, in order to provide reference for expanding the research and application of amphibian bioactive peptides.