Inhibition of α-glucosidase activity and intestinal glucose transport to assess the <i>in vivo</i> anti-hyperglycemic potential of dodecyl-acylated phlorizin and polydatin derivatives
Zhengming Xu, Kseniya Hileuskaya, Aliaksandr Kraskouski, Yujiao Yang, Zhe Huang, Zhengang Zhao
Abstract
Dodecyl phlorizin and polydatin derivatives are safe and promising in vivo hypoglycemic active compounds that can inhibit the hydrolytic activity of α-glucosidase and intestinal glucose absorption.
Topics & Concepts
PhlorizinIn vivoChemistryGlucose transporterPharmacologyBiochemistryGlucose uptakeInternal medicineMedicineBiologyInsulinBiotechnologyNatural Antidiabetic Agents StudiesEnzyme Catalysis and ImmobilizationPhytochemicals and Antioxidant Activities