Litcius/Paper detail

How the amino acid leucine activates the key cell-growth regulator mTOR

Tibor Vellai

2021Nature54 citationsDOI

Topics & Concepts

mTORC1LeucineRegulatorAmino acidPI3K/AKT/mTOR pathwayCell growthCell biologyChemistryNutrient sensingBiochemistryBiologySignal transductionGenePI3K/AKT/mTOR signaling in cancerCancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways