Predictive Factors for Pneumomediastinum During Management of Connective Tissue Disease-related Interstitial Lung Disease: A Retrospective Study
Shota Okamoto, Hiroto Tsuboi, Hisashi Noma, Daiki Tabuchi, Toshiki Sugita, Taihei Nishiyama, Toshihiko Terasaki, Masaru Shimizu, Fumika Honda, Mizuki Yagishita, Ayako Ohyama, Izumi Kurata, Saori Abe, Hiroyuki Takahashi, Atsumu Osada, Shinya Hagiwara, Yuya Kondo, Isao Matsumoto, Takayuki Sumida
Abstract
and 378 U/L, respectively. LDH showed a sensitivity of 61.5% and the highest specificity of 87.8%. Importantly, combining these markers resulted in the highest sensitivity of 100% and a specificity of 71.4%. Conclusion A low BMI and high serum LDH levels at baseline are useful predictive factors for pneumomediastinum development in CTD-ILD patients.
Topics & Concepts
MedicinePneumomediastinumInterstitial lung diseaseConnective tissue diseaseRetrospective cohort studyConnective tissuePathologyDiseaseLungRadiologyInternal medicinePneumothoraxAutoimmune diseasePneumothorax, Barotrauma, EmphysemaInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisPleural and Pulmonary Diseases