Chlorpyrifos induces cell proliferation in MCF-7 and MDA-MB-231 cells, through cholinergic and Wnt/β-catenin signaling disruption, AChE-R upregulation and oxidative stress generation after single and repeated treatment
Paula Moyano, José Manuel García, Jimena García, Adela Pelayo, Pilar Muñoz-Calero, María Teresa Frejo, María José Anadón, María Victoria Naval, Andrea Flores, Vega Alejandra Mirat, Javier del Pino
Topics & Concepts
Wnt signaling pathwayOxidative stressAcetylcholinesteraseCell growthDownregulation and upregulationMCF-7ChemistryCell biologyAcetylcholineReactive oxygen speciesSignal transductionEndocrinologyInternal medicineCancer cellCancer researchBiologyBiochemistryCancerMedicineEnzymeHuman breastGeneCholinesterase and Neurodegenerative DiseasesPesticide Exposure and ToxicityGlutathione Transferases and Polymorphisms