Role of HSP70 chaperone in protein aggregate phenomenon of GNE mutant cells: Therapeutic lead for GNE Myopathy
Rashmi Yadav, Shamulailatpam Shreedarshanee Devi, Jyoti Oswalia, Sivaprakash Ramalingam, Ranjana Arya
Topics & Concepts
Sialic acidMutantChaperone (clinical)Hsp70PhenotypeBiologyActivator (genetics)HEK 293 cellsProtein aggregationAmyloid diseaseMutationMyopathyCancer researchCell biologyHeat shock proteinGeneBiochemistryGeneticsDiseaseMedicinePathologyAmyloid fibrilAmyloid βInflammatory Myopathies and DermatomyositisCardiomyopathy and Myosin StudiesMuscle Physiology and Disorders