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An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer

Paula Voabil, Marjolein de Bruijn, Lisanne M. Roelofsen, Sanne H. Hendriks, Simone Brokamp, Marlous van den Braber, Annegien Broeks, Joyce Sanders, Petra Herzig, Alfred Zippelius, Christian U. Blank, Koen J. Hartemink, Kim Monkhorst, John B.A.G. Haanen, Ton N. Schumacher, Daniela S. Thommen

2021Nature Medicine369 citationsDOI

Topics & Concepts

Ex vivoBlockadeImmune systemIn vivoCancer researchCancerImmune checkpointBiologyImmunologyMedicineImmunotherapyReceptorInternal medicineBiotechnologyCancer Immunotherapy and BiomarkersImmune cells in cancerCAR-T cell therapy research
An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer | Litcius