Ferroptosis-induced anticancer effect of resveratrol with a biomimetic nano-delivery system in colorectal cancer treatment
Ziting Zhang, You Ji, Nan Hu, Qinqi Yu, Xinrui Zhang, Jie Li, Fenglei Wu, Huae Xu, Qiyun Tang, Xiaolin Li
Abstract
study demonstrated an excellent treatment efficacy for CRC. Altogether, our study highlighted the therapeutic potential of RSV as a ferroptosis-inducing anticancer agent and when loaded into a biomimetic nanoplatform, it might pave the way for the application of RSV loaded nanosystems for colorectal cancer treatment.
Topics & Concepts
NanocarriersChemistryLipid peroxidationGPX4ResveratrolCancer cellReactive oxygen speciesHeLaDrug deliveryCancer researchNanocapsulesProgrammed cell deathCancerPharmacologyApoptosisOxidative stressBiochemistryCellNanotechnologyGlutathione peroxidaseNanoparticleMedicineCatalaseMaterials scienceOrganic chemistryInternal medicineFerroptosis and cancer prognosisNanoplatforms for cancer theranosticsMicroRNA in disease regulation