Rationale design, synthesis, cytotoxicity evaluation, and<i>in silico</i>mechanistic studies of novel 1,2,3-triazoles with potential anticancer activity
Esraa M. Othman, Eman A. Fayed, Ebtehal M. Husseiny, Hamada S. Abulkhair
Abstract
A new set of 1,2,3-triazoles was designed and synthesized to evaluate their potential to inhibit the growth of cancer cells.
Topics & Concepts
ChemistryIn silicoCytotoxicityCombinatorial chemistryComputational biologyStereochemistryBiochemistryIn vitroGeneBiologyClick Chemistry and ApplicationsSynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds