Embedding an extraordinary amount of gemifloxacin antibiotic in ZIF-8 framework with one-step synthesis and measurement of its H<sub>2</sub>O<sub>2</sub>-sensitive release and potency against infectious bacteria
Sajjad Soltani, Kamran Akhbari
Abstract
GEM@ZIF-8 has DLC = 69.82% and DLE = 89.03%, with controlled release dependent on H 2 O 2 concentration, and it shows significant antibacterial activity.
Topics & Concepts
ChemistryGemifloxacinPotencyEmbeddingAntibioticsStereochemistryCombinatorial chemistryNanotechnologyAntibacterial agentBiochemistryIn vitroMaterials scienceComputer scienceArtificial intelligenceNanoplatforms for cancer theranosticsMetal-Organic Frameworks: Synthesis and ApplicationsLuminescence and Fluorescent Materials