Integrated experimental/computational approaches to characterize the systems formed by vanadium with proteins and enzymes
Giuseppe Sciortino, Jean‐Didier Maréchal, Eugenio Garribba
Abstract
An integrated instrumental/computational approach to characterize metallodrug–protein adducts at the molecular level is reviewed. A series of applications are described, focusing on potential vanadium drugs with a generalization to other metals.
Topics & Concepts
VanadiumGeneralizationChemistryAdductEnzymeComputational chemistryCombinatorial chemistryOrganic chemistryMathematicsMathematical analysisVanadium and Halogenation ChemistryMetal-Catalyzed Oxygenation MechanismsTrace Elements in Health