Mitochondrial hyperfusion induces metabolic remodeling in lung endothelial cells by modifying the activities of electron transport chain complexes I and III
Manivannan Yegambaram, Xutong Sun, Qing Lü, Yan Jin, Wojciech Ornatowski, Jamie Soto, Saurabh Aggarwal, Ting Wang, Kim Tieu, Haiwei Gu, Jeffrey R. Fineman, Stephen M. Black
Topics & Concepts
MFN2MFN1Mitochondrial fissionFIS1mitochondrial fusionCell biologyMitochondrionBiologyBioenergeticsChemistryBiochemistryMitochondrial DNAGenePulmonary Hypertension Research and TreatmentsMitochondrial Function and PathologyNitric Oxide and Endothelin Effects