The anti-inflammatory and analgesic effects of intraperitoneal melatonin after spinal nerve ligation are mediated by inhibition of the NF-κB/NLRP3 inflammasome signaling pathway
Yihao Wang, Yuru Tang, Xiao Gao, Juan Liu, Nannan Zhang, Zhaojun Liang, Yan Li, Li-xiao Pan
Topics & Concepts
MelatoninNeuropathic painPharmacologyAnalgesicMedicineIntraperitoneal injectionInflammasomeTumor necrosis factor alphaLumbar Spinal CordCaspase 1Spinal cordInterleukinInflammationAnesthesiaEndocrinologyInternal medicineCytokinePsychiatryCircadian rhythm and melatoninPain Mechanisms and TreatmentsSleep and Wakefulness Research