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Apigenin enhances Nrf2-induced chaperone-mediated autophagy and mitigates α-synuclein pathology: Implications for Parkinson's disease therapy

Yibin Huang, Lulu Tian, Ziwen Zhu, Kai-Ge Zhou, Xue Lai, Yan-Zi Peng, Wu Zhuang, Weifang Tong, Huan Wang, Xijin Wang, Qiang Guan, Lingjing Jin, Ya Feng, Weiyu Weng, Jing-Xing Zhang

2025Phytomedicine16 citationsDOI

Topics & Concepts

AutophagyApigeninAlpha-synucleinParkinson's diseaseDiseaseChemistryChaperone (clinical)Cell biologyMedicineCancer researchBiologyPathologyBiochemistryFlavonoidApoptosisAntioxidantParkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease
Apigenin enhances Nrf2-induced chaperone-mediated autophagy and mitigates α-synuclein pathology: Implications for Parkinson's disease therapy | Litcius