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Rifampicin-induced ER stress and excessive cytoplasmic vacuolization instigate hepatotoxicity via alternate programmed cell death paraptosis in vitro and in vivo

KM Kainat, Mohammad Imran Ansari, Nuzhat Bano, Pankaj Jagdale, Anjaneya Ayanur, Mahadeo Kumar, Pradeep Kumar Sharma

2023Life Sciences23 citationsDOI

Topics & Concepts

Unfolded protein responsePharmacologyVacuolizationIn vivoViability assayProgrammed cell deathAlanine transaminaseLiver injuryChemistryBiologyApoptosisBiochemistryEndocrinologyBiotechnologyDrug-Induced Hepatotoxicity and ProtectionEndoplasmic Reticulum Stress and DiseaseAutophagy in Disease and Therapy
Rifampicin-induced ER stress and excessive cytoplasmic vacuolization instigate hepatotoxicity via alternate programmed cell death paraptosis in vitro and in vivo | Litcius