Physiologically based pharmacokinetic (PBPK) modeling of meloxicam in different CYP2C9 genotypes
Chang‐Keun Cho, Hye-Jung Park, Pureum Kang, Sungmin Moon, Yun Jeong Lee, Jung‐Woo Bae, Choon‐Gon Jang, Seok‐Yong Lee
Topics & Concepts
Physiologically based pharmacokinetic modellingMeloxicamCYP2C9PharmacokineticsPharmacologyDosingCYP3A4GenotypeMedicineChemistryCytochrome P450Internal medicineBiochemistryMetabolismGenePharmacogenetics and Drug MetabolismInflammatory mediators and NSAID effectsDrug Transport and Resistance Mechanisms