An electrochemical SARS-CoV-2 biosensor inspired by glucose test strip manufacturing processes
Vincent Vezza, Adrian Butterworth, Perrine Lasserre, Ewen O. Blair, Alexander MacDonald, Stuart Hannah, Christopher Rinaldi, Paul A. Hoskisson, Andrew C. Ward, Alistair Longmuir, Steven Setford, Eoghan C. W. Farmer, Michael E. Murphy, Damion K. Corrigan
Abstract
Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The test provides a scalable route to sensitive, specific, rapid and low cost mass testing.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)Biosensor2019-20 coronavirus outbreakElectrochemistryLayer (electronics)NanotechnologyVirologyMaterials scienceChemistryElectrodeMedicineInfectious disease (medical specialty)Internal medicineOutbreakDiseasePhysical chemistrySARS-CoV-2 detection and testingAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection