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Case Report: Recurrence of Positive SARS-CoV-2 Results in Patients Recovered From COVID-19

Ren-zi Zhang, Wang Deng, Jing He, Yuyan Song, Chunfang Qian, Qian Yu, Daoxin Wang

2020Frontiers in Medicine13 citationsDOIOpen Access PDF

Abstract

Background: Coronavirus disease 2019 (COVID-19) is spreading throughout the world. Limited data are available for recurrence of positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) results in patients with long duration of COVID-19. Methods: We reported four cases recovered from COVID-19 with recurrence of positive SARS-CoV-2 results during the long-term follow-up. Results: The four patients recovered from COVID-19 showed recurrence of positive SARS-CoV-2 results for more than 120 days with no symptoms and normal chest CT scan. Conclusions: The dynamic surveillance of SARS-CoV-2 by nucleic acid detection and serological assays is important for asymptomatic patients who might be potentially infectious.

Topics & Concepts

AsymptomaticCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Medicine2019-20 coronavirus outbreakCoronavirusSerologyInternal medicineVirologyDiseaseInfectious disease (medical specialty)ImmunologyOutbreakAntibodyCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 ResearchSARS-CoV-2 detection and testing