Combination of hyaluronic acid conjugates with immunogenic cell death inducer and CpG for glioblastoma local chemo-immunotherapy elicits an immune response and induces long-term survival
Giuseppina Catania, Giulia Rodella, Kévin Vanvarenberg, Véronique Préat, Alessio Malfanti
Topics & Concepts
Immunogenic cell deathCpG OligodeoxynucleotideCancer researchChemoimmunotherapyTumor microenvironmentImmune systemHyaluronic acidImmunotherapyDoxorubicinCD8MicrogliaGliomaDrug deliveryMedicineDendritic cellNanocarriersPharmacologyImmunologyBiologyChemistryDrugInflammationChemotherapyInternal medicineGeneOrganic chemistryDNA methylationGene expressionAnatomyBiochemistryImmune cells in cancerImmunotherapy and Immune ResponsesNanoplatforms for cancer theranostics