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Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy

Adrián Álvarez-Varela, Laura Novellasdemunt, Francisco M. Barriga, Xavier Hernando‐Momblona, Adrià Cañellas‐Socias, Sara Cano-Crespo, Marta Sevillano, Carme Cortina, Diana Stork, Clara Morral, Gemma Turón, Felipe Slebe, Laura Jiménez-Gracia, Ginevra Caratù, Peter Jung, Giorgio Stassi, Holger Heyn, Daniele V. F. Tauriello, Lídia Mateo, Sabine Tejpar, Elena Sancho, Camille Stephan‐Otto Attolini, Eduard Batlle

2022Nature Cancer134 citationsDOI

Topics & Concepts

LGR5BiologyCancer stem cellColorectal cancerStem cellOrganoidChemotherapyWnt signaling pathwayCancer researchPopulationProgenitor cellCancer cellCancerImmunologyMedicineCell biologyGeneticsSignal transductionEnvironmental healthCancer Cells and MetastasisHippo pathway signaling and YAP/TAZFOXO transcription factor regulation
Mex3a marks drug-tolerant persister colorectal cancer cells that mediate relapse after chemotherapy | Litcius