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Mutant IDH1 inhibitors activate pSTAT3-Y705 leading to an increase in BCAT1 and YKL-40 levels in mutant IDH1-expressing cells

Debanjan Bhattacharjee, Balabhaskararao Kancharana, Nishant Jain

2021Biochimica et Biophysica Acta (BBA) - Molecular Cell Research15 citationsDOI

Topics & Concepts

MutantSTAT3IDH1Gene knockdownCancer researchCell growthChemistryBiologyPhosphorylationCell biologyCell cultureBiochemistryGeneticsGeneGlioma Diagnosis and TreatmentMicroRNA in disease regulationEpigenetics and DNA Methylation
Mutant IDH1 inhibitors activate pSTAT3-Y705 leading to an increase in BCAT1 and YKL-40 levels in mutant IDH1-expressing cells | Litcius