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tidytof: a user-friendly framework for scalable and reproducible high-dimensional cytometry data analysis

Timothy Keyes, Abhishek Koladiya, Yu‐Chen Lo, Garry P. Nolan, Kara L. Davis

2023Bioinformatics Advances14 citationsDOIOpen Access PDF

Abstract

Summary: While many algorithms for analyzing high-dimensional cytometry data have now been developed, the software implementations of these algorithms remain highly customized-this means that exploring a dataset requires users to learn unique, often poorly interoperable package syntaxes for each step of data processing. To solve this problem, we developed {tidytof}, an open-source R package for analyzing high-dimensional cytometry data using the increasingly popular 'tidy data' interface. Availability and implementation: {tidytof} is available at https://github.com/keyes-timothy/tidytof and is released under the MIT license. It is supported on Linux, MS Windows and MacOS. Additional documentation is available at the package website (https://keyes-timothy.github.io/tidytof/). Supplementary information: online.

Topics & Concepts

Computer scienceInteroperabilityScalabilityDocumentationSoftwareMIT LicenseInterface (matter)LicenseImplementationUser FriendlyDatabaseWorld Wide WebOperating systemSoftware engineeringBubbleMaximum bubble pressure methodSingle-cell and spatial transcriptomicsCell Image Analysis TechniquesAdvanced Electron Microscopy Techniques and Applications
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