Preparation and evaluation of soluble epoxide hydrolase inhibitors with improved physical properties and potencies for treating diabetic neuropathic pain
Kin Sing Stephen Lee, Jen C. Ng, Jun Yang, Sung‐Hee Hwang, Christophe Morisseau, Karen Wagner, Bruce D. Hammock
Topics & Concepts
Epoxide hydrolase 2ChemistryPharmacophorePotencyIn vivoPharmacologyUreaEnzymeIn vitroStereochemistryBiochemistryMedicineBiotechnologyBiologyEicosanoids and Hypertension PharmacologyAlcohol Consumption and Health EffectsHormonal Regulation and Hypertension