Statistical Optimizing of Medium for Clavulanic Acid Production by Streptomyces clavuligerus Using Response Surface Methodology
Feng Tao, Jie Zhao, Ju Chu, Yonghong Wang, Yingping Zhuang
Topics & Concepts
Streptomyces clavuligerusTrioleinFermentationResponse surface methodologyDextrinClavulanic acidGlycerolBox–Behnken designChemistryFractional factorial designFood scienceBranFactorial experimentChromatographyBiochemistryMathematicsAntibioticsOrganic chemistryEnzymeLipaseRaw materialStarchAmoxicillinStatisticsMicrobial Natural Products and BiosynthesisPlant Disease Resistance and GeneticsMycobacterium research and diagnosis