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Contribution of T cell subsets to different food allergic diseases

Lisa Hung, Brianna Zientara, M. Cecilia Berin

2024Immunological Reviews14 citationsDOIOpen Access PDF

Abstract

Food allergies occur due to a lack of tolerance to the proteins found in foods. While IgE- and non-IgE-mediated food allergies have different clinical manifestations, epidemiology, pathophysiology, and management, they share dysregulated T cell responses. Recent studies have shed light on the contributions of different T cell subsets to the development and persistence of different food allergic diseases. This review discusses the role of T cells in both IgE- and non-IgE-mediated food allergies and considers the potential future investigations in this context.

Topics & Concepts

BiologyImmunologyLymphocyte subsetsT cellImmune systemFood Allergy and Anaphylaxis ResearchEosinophilic EsophagitisAsthma and respiratory diseases
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