Litcius/Paper detail

Successful contact tracing systems for COVID-19 rely on effective quarantine and isolation

Alex James, Michael J. Plank, Shaun C. Hendy, Rachelle N. Binny, Audrey Lustig, Nicholas Steyn, Annette Nesdale, Ayesha J Verrall

2021PLoS ONE37 citationsDOIOpen Access PDF

Abstract

Models of contact tracing often over-simplify the effects of quarantine and isolation on disease transmission. We develop a model that allows us to investigate the importance of these factors in reducing the effective reproduction number. We show that the reduction in onward transmission during quarantine and isolation has a bigger effect than tracing coverage on the reproduction number. We also show that intuitively reasonable contact tracing performance indicators, such as the proportion of contacts quarantined before symptom onset, are often not well correlated with the reproduction number. We conclude that provision of support systems to enable people to quarantine and isolate effectively is crucial to the success of contact tracing.

Topics & Concepts

Contact tracingQuarantineCoronavirus disease 2019 (COVID-19)Isolation (microbiology)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Tracing2019-20 coronavirus outbreakTransmission (telecommunications)Basic reproduction numberReproductionComputer sciencePandemicBiologyMedicineVirologyDiseaseInfectious disease (medical specialty)TelecommunicationsBioinformaticsEnvironmental healthEcologyOutbreakOperating systemPopulationPathologyCOVID-19 epidemiological studiesCOVID-19 Digital Contact TracingData-Driven Disease Surveillance