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Synthesis of naphthalimide-phenanthro[9,10-d]imidazole derivatives: In vitro evaluation, binding interaction with DNA and topoisomerase inhibition

Iqubal Singh, Vijay Luxami, Kamaldeep Paul

2020Bioorganic Chemistry46 citationsDOI

Topics & Concepts

TopoisomeraseChemistryDNACytotoxicityImidazoleDocking (animal)StereochemistryIntercalation (chemistry)In vitroBinding constantConjugateBinding siteBiochemistryOrganic chemistryNursingMathematicsMedicineMathematical analysisCancer therapeutics and mechanismsSynthesis and Biological EvaluationBioactive Compounds and Antitumor Agents
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