An E3 ligase network engages GCN1 to promote the degradation of translation factors on stalled ribosomes
Keely Oltion, Jordan D. Carelli, Tangpo Yang, Stephanie K. See, Hao‐Yuan Wang, Martin Kampmann, Jack Taunton
Topics & Concepts
BiologyRibosomeUbiquitin ligaseUbiquitinCell biologyRibosomal proteinTranslation (biology)ProteostasisRibosomal RNARibosome profilingGeneticsMessenger RNAGeneRNARNA and protein synthesis mechanismsRNA modifications and cancerPeptidase Inhibition and Analysis