Neuronal Nitric Oxide Synthase (nNOS) uncoupling in ischemic stroke: Mechanisms of oxidative/nitrosative stress and opportunities for neuroprotection: A review
Aleena Anwar, Daraksha Yameen, Mohammad Masood, Suhel Parvez, Mohammad Mahfuzul Haque
Topics & Concepts
Oxidative stressNitric oxideIschemiaNitric oxide synthasePremovement neuronal activityNeuroscienceMitochondrionPharmacologyInflammationCerebral blood flowChemistryIschemic injuryCentral nervous systemMedicineStroke (engine)Ischemic strokeNeuroprotectionReceptorNOS1MediatorNeurotransmissionBrain ischemiaAntioxidantOxidative phosphorylationNeuroinflammationSignal transductionNeuronCell biologyReperfusion injuryNeuronal damageNeuronal Nitric Oxide SynthaseReactive oxygen speciesBiologyHomeostasisBlood–brain barrierEndothelial dysfunctionEndotheliumNitric Oxide and Endothelin EffectsElectron Spin Resonance StudiesNeurological Disease Mechanisms and Treatments