Improving the colloidal stability of protein@ZIF-8 nanoparticles in biologically relevant buffers
Justin Van Houten, Ruben Castillo Barberi, Jared M. D. King, Alana F. Ogata
Abstract
ZIF-8 is a metal–organic framework frequently used for biomedical and analytical applications. Colloidal stability of ZIF-8 biocomposites in biologically relevant buffers is a challenge. We present strategies to improve colloidal stability of protein@ZIF-8 nanoparticles in buffers and cell media.
Topics & Concepts
ColloidNanoparticleProtein stabilityMaterials scienceNanotechnologyChemical engineeringChemistryEngineeringBiochemistryNanoparticle-Based Drug DeliveryInnovative Microfluidic and Catalytic Techniques InnovationProtein purification and stability