Litcius/Paper detail

Identification of Cyclohexadienyl Hydrides as Intermediates in Molybdenum‐Catalyzed Arene Hydrogenation

Gabriele Hierlmeier, Paolo Tosatti, Kurt Puentener, Paul J. Chirik

2022Angewandte Chemie International Edition18 citationsDOI

Abstract

Abstract Treatment of phosphino(imino)pyridine (PIP) molybdenum cyclooctadiene (COD) complexes [(PIP)Mo(COD)] with dihydrogen in the presence of benzene selectively furnished the molybdenum cyclohexadienyl hydrides [(PIP)MoH( η 5 ‐C 6 H 7 )], which are precatalysts for the hydrogenation of benzene to cyclohexane. [(PIP)MoH( η 5 ‐C 6 H 7 )] arises from a rarely observed insertion of benzene into a molybdenum‐hydride bond, a key step in the molybdenum‐catalyzed homogeneous hydrogenation of arenes. The reaction with toluene afforded a single isomer of the corresponding molybdenum cyclohexadienyl hydride while para ‐xylene predominantly formed the molybdenum η 6 ‐arene complex with the insertion product being a minor component. Addition of carbon monoxide to a cyclohexane‐ d 12 solution of [(PIP)MoH( η 5 ‐C 6 H 7 )] liberated cyclohexadiene, providing experimental support for a higher kinetic barrier for the subsequent steps en route to cycloalkanes.

Topics & Concepts

MolybdenumChemistryBenzeneHydrideTolueneCatalysisCyclohexaneMedicinal chemistryPyridinePhotochemistryOrganic chemistryHydrogenAsymmetric Hydrogenation and CatalysisOrganometallic Complex Synthesis and CatalysisCarbon dioxide utilization in catalysis