ALS skin fibroblasts reveal oxidative stress and ERK1/2-mediated cytoplasmic localization of TDP-43
Nicla Romano, Alessia Catalani, Serena Lattante, Antonio Belardo, Silvia Proietti, Laura Bertini, Federica Silvestri, Elisabetta Catalani, Davide Cervia, Lello Zolla, Mario Sabatelli, Kristy Welshhans, Marcello Ceci
Topics & Concepts
Stress granuleAmyotrophic lateral sclerosisCytoplasmOxidative stressCell biologyFibroblastC9orf72BiologyPhosphorylationmTORC1Oxidative phosphorylationChemistryGeneCell cultureGeneticsPathologyBiochemistryMedicineProtein kinase BTrinucleotide repeat expansionMessenger RNADiseaseTranslation (biology)AlleleAmyotrophic Lateral Sclerosis ResearchParkinson's Disease Mechanisms and TreatmentsNeurogenetic and Muscular Disorders Research