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HOMA-IR for predicting clinical pregnancy rate during IVF

Haixia Song, Zhenqing Yu, Ping Li, Ying Wang, Yuhua Shi

2021Gynecological Endocrinology26 citationsDOI

Abstract

OBJECTIVE: To determine the cutoff values of HOMA-IR for predicting clinical pregnancy rate in normal weight patients during their first IVF. MATERIALS AND METHODS: who received first IVF-ET during the period from December 2018 to June 2019.We assessed the associations between HOMA-IR and clinical pregnancy rates during IVF in the women with or without PCOS according to different BMI ranges. RESULTS: , clinical pregnancy rate was declined significantly at the HOMA-IR > 3.15 (OR, 0.186; 95% CI, 0.04-0.872). CONCLUSION: HOMA-IR and BMI had adverse effects on the IVF outcome of infertility women. Moreover, obesity can increase the degree of insulin resistance in infertility women. These findings suggested that only better HOMA-IR and BMI will lead to better IVF results.

Topics & Concepts

PregnancyMedicinePregnancy rateBody mass indexInternal medicineObstetricsGastroenterologyGynecologyBiologyGeneticsOvarian function and disordersGestational Diabetes Research and ManagementReproductive System and Pregnancy
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