Novel solid-contact ion-selective electrode based on a polyaniline transducer layer for determination of alcaftadine in biological fluid
Ola G. Hussein, Dina A. Ahmed, M. A. Abdelkawy, Mamdouh R. Rezk, Amr M. Mahmoud, Yasmin Rostom
Abstract
detection limit. The selectivity and capabilities of the formed alcaftadine sensor were tested in the presence of its pharmaceutical formulation excipients as well as its degradation products. Additionally, the sensor was capable of quantifying the studied drug in a rabbit aqueous humor. Method's greenness profile was evaluated by the means of Analytical Greenness (AGREE) metric assessment tool.
Topics & Concepts
PolyanilineElectrodeMaterials scienceLayer (electronics)TransducerGlassy carbonIonSubstrate (aquarium)FabricationAnalytical Chemistry (journal)ElectrochemistryChemical engineeringNanotechnologyChemistryChromatographyCyclic voltammetryComposite materialPolymerOrganic chemistryMedicinePhysical chemistryGeologyEngineeringAlternative medicinePhysicsOceanographyPolymerizationPathologyQuantum mechanicsAnalytical Chemistry and SensorsElectrochemical sensors and biosensorsElectrochemical Analysis and Applications