Modeling large-volume subcutaneous injection of monoclonal antibodies with anisotropic porohyperelastic models and data-driven tissue layer geometries
Mario de Lucio, Yu Leng, Atharva Hans, Ilias Bilionis, Melissa C. Brindise, Arezoo M. Ardekani, Pavlos P. Vlachos, Héctor Gómez
2022Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials30 citationsDOI
Topics & Concepts
PoromechanicsLeverage (statistics)Subcutaneous tissueMonoclonal antibodySubcutaneous injectionBiomedical engineeringFinite volume methodMaterials scienceAnisotropyMechanicsMedicineComputer scienceAntibodyPathologyComposite materialPhysicsImmunologyInternal medicinePorous mediumQuantum mechanicsPorosityMachine learningBotulinum Toxin and Related Neurological DisordersAdvanced Numerical Analysis TechniquesCellular Mechanics and Interactions