Recombinant snake antivenoms get closer to the clinic
Andreas H. Laustsen
Abstract
Snakebite envenomings kill ~100 000 victims each year and leave many more with permanent sequelae. Antivenoms have been available for more than 125 years but are in need of innovation. A new study by Khalek et al. highlights broadly neutralizing human monoclonal antibodies (mAbs) that might be used to develop recombinant antivenoms with superior therapeutic benefits.
Topics & Concepts
Monoclonal antibodyMedicineRecombinant DNAImmunologyIntensive care medicineBiologyAntibodyGeneBiochemistryVenomous Animal Envenomation and StudiesRabies epidemiology and controlBiochemical and Structural Characterization