Structural insights into the co-aggregation of Aβ and tau amyloid core peptides: Revealing potential pathological heterooligomers by simulations
Xuhua Li, Yujie Chen, Zhiwei Yang, Shengli Zhang, Guanghong Wei, Lei Zhang
Topics & Concepts
ChemistryFibrilAmyloid fibrilBiophysicsProtein aggregationAmyloid (mycology)StackingMolecular dynamicsBeta sheetPeptideBiochemistryAmyloid βBiologyDiseasePathologyComputational chemistryInorganic chemistryMedicineOrganic chemistryAlzheimer's disease research and treatmentsProtein Structure and DynamicsComputational Drug Discovery Methods