Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes
Jae‐Won Lee, Elise S. Cowley, Patricia G. Wolf, Heidi L. Doden, Tsuyoshi Murai, Kelly Yovani Olivos Caicedo, Lindsey K. Ly, Fu-Rong Sun, Hajime Takei, Hiroshi Nittono, Steven L. Daniel, Isaac Cann, H. Rex Gaskins, Karthik Anantharaman, João M. P. Alves, Jason M. Ridlon
Abstract
among Firmicutes in human metagenomes, demonstrating an increased abundance of the two genes in colorectal cancer (CRC) patients relative to healthy individuals.
Topics & Concepts
Lithocholic acidDeoxycholic acidFirmicutesCholic acidChenodeoxycholic acidBile acidBiologyBiochemistryBacteroidetesGut floraGene16S ribosomal RNADrug Transport and Resistance MechanismsPediatric Hepatobiliary Diseases and TreatmentsHelicobacter pylori-related gastroenterology studies